After reserving their dream wedding package at Niagara Falls, Dean and Darren learn they've booked themselves in a run-down motor lodge sandwiched between two chemical plants run by some guy named Shibbawitz and a Burmese refugee family.

　　一栋老旧楼房顶层的简陋公寓中，住着两个为了艺术而挣扎的室友：罗杰(Adam Pascal 亚当•帕斯考 饰)和马克（Anthony Rapp 安东尼•雷普 饰）。马克最近失恋了，他的女友莫琳因为喜欢同性的乔安妮而抛弃了他。　　马克之前的另一位室友汤姆(Jesse L. Martin 杰西•L•马丁 饰)――一个电脑奇才，也是艾滋病毒的携带者，不幸路遇抢劫，遍体鳞…